Quinolines and derivatives

Medchemexpress LLC 7-Bromoquinoline | 4965-36-0 | 208.06 | 25 G

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7-Bromoquinoline is a biochemical reagent that serves as an organic compound for various life science research applications. It has a high purity of 99.95%.

• Used as a biological material
• Used as an organic compound for life science related research
• Molecular formula: C9H6BrN
• Appears as a solid below 32°C and liquid above 36°C
• Light yellow to yellow color

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Medchemexpress LLC 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaheptatriacontan-1-amine | 1977493-48-3 | >98.0% | 559.69 | C25H53NO12 | 50 MG

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m-PEG12-amine is a methoxy-terminated polyethylene glycol (PEG) linker with a terminal primary amine used as a hydrophilic spacer for bioconjugation, PROTAC, and ADC linker synthesis. It provides aqueous solubility and a reactive amine for standard coupling chemistries.

• Methoxy-terminated PEG12 spacer provides hydrophilicity.
• Terminal primary amine enables standard coupling chemistry.
• High purity: >98.0%.
• Molecular weight approximately 559.69.
• Appearance: colorless to off-white solid-liquid mixture.
• Storage: store at -20°C, protect from light, under nitrogen.

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Medchemexpress LLC Azido-PEG1-amine | 464190-91-8 | ≥98.0% | C4H10N4O | 100 MG

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Azido-PEG1-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs utilize two ligands connected by a linker to target an E3 ubiquitin ligase and a protein of interest, facilitating selective degradation via the intracellular ubiquitin-proteasome system.

• PEG-based PROTAC linker
• Functions as a click chemistry reagent
• Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
• Utilized in PROTAC synthesis
• Relevant for cancer targeted therapy

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Medchemexpress LLC 38-azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontan-1-amine | 2803478-25-1 | 98.0% | 614.73 g/mol | C26H54N4O12 | 25 MG

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Azido-PEG12-amine is a PEG-based bifunctional linker with an azide at one terminus and a primary amine at the other. It functions as a water-soluble spacer (approximately 12 ethylene glycol units) used in click chemistry, bioconjugation, PROTAC and ADC linker design.

• Azide and primary amine functional groups enable click chemistry and amide coupling.
• Approximately 12 ethylene glycol units provide flexible, hydrophilic spacing.
• Molecular weight 614.73 g/mol for predictable linker length and mass.
• Purity 98.0% (NMR) as supplied in certificate of analysis.
• Colorless to light yellow liquid physical form for ease of handling.
• Stable when stored sealed and protected from moisture and light; in solvent: -80°C (6 months) or -20°C (1 month).

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eMolecules​ 1255942-06-3 | DBCO-amine | Ambeed | MFCD22380759 | 276.339 | C18H16N2O | 98.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 801464926

DBCO-amine | Ambeed | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 98.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 801464926

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Medchemexpress LLC Azido-PEG2-C2-amine | 166388-57-4 | MFCD13189985 | >97.0% | 174.20 g·mol⁻¹ | C6H14N4O2 | 100 MG

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Azido-PEG2-C2-amine is a PEG-based bifunctional linker bearing an azide and a primary amine. It is used as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and as a linker in PROTAC and antibody-drug conjugate (ADC) synthesis.

• Azide functional group for click chemistry (CuAAC and SPAAC).
• Primary amine for conjugation to carboxyl and activated ester groups.
• PEG2 spacer provides water solubility and flexible linker length.
• Typically supplied as a solid suitable for standard conjugation workflows.
• Reported purity >97.0% and molecular weight 174.20 g·mol⁻¹.

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